Early postnatal microglial ablation in the Ccdc39 mouse model reveals adverse effects on brain development and in neonatal hydrocephalus

BACKGROUND: Neonatal hydrocephalus is a congenital abnormality resulting in an inflammatory response and microglial cell activation both clinically and in animal models. Previously, we reported a mutation in a motile cilia gene, Ccdc39 that develops neonatal progressive hydrocephalus (prh) with infl...

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Detalles Bibliográficos
Autores principales: Brown, Farrah N., Iwasawa, Eri, Shula, Crystal, Fugate, Elizabeth M., Lindquist, Diana M., Mangano, Francesco T., Goto, June
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251678/
https://www.ncbi.nlm.nih.gov/pubmed/37296418
http://dx.doi.org/10.1186/s12987-023-00433-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251678/
https://www.ncbi.nlm.nih.gov/pubmed/37296418
http://dx.doi.org/10.1186/s12987-023-00433-4

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