TREM2 Agonism with a Monoclonal Antibody Attenuates Tau Pathology and Neurodegeneration

TREM2 is a membrane receptor expressed on microglia that plays a pivotal role in the organization and function of these innate immune cell components within the neurodegenerated brain. Whereas TREM2 deletion has been studied extensively in experimental beta-amyloid and Tau-based models of Alzheimer’...

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Detalles Bibliográficos
Autores principales: Fassler, Michael, Benaim, Clara, George, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252191/
https://www.ncbi.nlm.nih.gov/pubmed/37296669
http://dx.doi.org/10.3390/cells12111549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252191/
https://www.ncbi.nlm.nih.gov/pubmed/37296669
http://dx.doi.org/10.3390/cells12111549

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