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TREM2 Agonism with a Monoclonal Antibody Attenuates Tau Pathology and Neurodegeneration
TREM2 is a membrane receptor expressed on microglia that plays a pivotal role in the organization and function of these innate immune cell components within the neurodegenerated brain. Whereas TREM2 deletion has been studied extensively in experimental beta-amyloid and Tau-based models of Alzheimer’...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252191/ https://www.ncbi.nlm.nih.gov/pubmed/37296669 http://dx.doi.org/10.3390/cells12111549 |