Impact of Short-Term (+)-JQ1 Exposure on Mouse Aorta: Unanticipated Inhibition of Smooth Muscle Contractility

(+)-JQ1, a specific chemical inhibitor of bromodomain and extraterminal (BET) family protein 4 (BRD4), has been reported to inhibit smooth muscle cell (SMC) proliferation and mouse neointima formation via BRD4 regulation and modulate endothelial nitric oxide synthase (eNOS) activity. This study aime...

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Detalles Bibliográficos
Autores principales: Yan, Binjie, Gui, Yu, Guo, Yanan, Sun, Jiaxing, Saifeddine, Mahmoud, Deng, Jingti, Hill, Joseph A., Hollenberg, Morley D., Jiang, Zhi-Sheng, Zheng, Xi-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252217/
https://www.ncbi.nlm.nih.gov/pubmed/37296583
http://dx.doi.org/10.3390/cells12111461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252217/
https://www.ncbi.nlm.nih.gov/pubmed/37296583
http://dx.doi.org/10.3390/cells12111461

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