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Impact of Short-Term (+)-JQ1 Exposure on Mouse Aorta: Unanticipated Inhibition of Smooth Muscle Contractility

(+)-JQ1, a specific chemical inhibitor of bromodomain and extraterminal (BET) family protein 4 (BRD4), has been reported to inhibit smooth muscle cell (SMC) proliferation and mouse neointima formation via BRD4 regulation and modulate endothelial nitric oxide synthase (eNOS) activity. This study aime...

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Detalles Bibliográficos
Autores principales:	Yan, Binjie, Gui, Yu, Guo, Yanan, Sun, Jiaxing, Saifeddine, Mahmoud, Deng, Jingti, Hill, Joseph A., Hollenberg, Morley D., Jiang, Zhi-Sheng, Zheng, Xi-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252217/ https://www.ncbi.nlm.nih.gov/pubmed/37296583 http://dx.doi.org/10.3390/cells12111461

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