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Development and Validation of a High-Performance Liquid Chromatography–Tandem Mass Spectrometry Method to Determine Promethazine and Its Metabolites in Edible Tissues of Swine

This study aimed to determine promethazine (PMZ) and its metabolites, promethazine sulfoxide (PMZSO) and monodesmethyl-promethazine (Nor(1)PMZ), in swine muscle, liver, kidney, and fat. A sample preparation method and high-performance liquid chromatography–tandem mass spectrometry (LC–MS/MS) analysi...

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Detalles Bibliográficos
Autores principales: Wen, Dehui, Shi, Rong, He, Haiming, Chen, Rundong, Zhang, Yingzi, Liu, Rong, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252443/
https://www.ncbi.nlm.nih.gov/pubmed/37297425
http://dx.doi.org/10.3390/foods12112180