Primary Ciliary Dyskinesia Patient-Specific hiPSC-Derived Airway Epithelium in Air-Liquid Interface Culture Recapitulates Disease Specific Phenotypes In Vitro

Primary ciliary dyskinesia (PCD) is a rare heterogenic genetic disorder associated with perturbed biogenesis or function of motile cilia. Motile cilia dysfunction results in diminished mucociliary clearance (MCC) of pathogens in the respiratory tract and chronic airway inflammation and infections su...

Descripción completa

Detalles Bibliográficos
Autores principales: von Schledorn, Laura, Puertollano Martín, David, Cleve, Nicole, Zöllner, Janina, Roth, Doris, Staar, Ben Ole, Hegermann, Jan, Ringshausen, Felix C., Nawroth, Janna, Martin, Ulrich, Olmer, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252476/
https://www.ncbi.nlm.nih.gov/pubmed/37296588
http://dx.doi.org/10.3390/cells12111467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252476/
https://www.ncbi.nlm.nih.gov/pubmed/37296588
http://dx.doi.org/10.3390/cells12111467

Ejemplares similares