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Broadly Applicable Control Approaches Improve Accuracy of ChIP-Seq Data

Chromatin ImmunoPrecipitation (ChIP) is a widely used method for the analysis of protein–DNA interactions in vivo; however, ChIP has pitfalls, particularly false-positive signal enrichment that permeates the data. We have developed a new approach to control for non-specific enrichment in ChIP that i...

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Detalles Bibliográficos
Autores principales: Petrie, Meghan V., He, Yiwei, Gan, Yan, Ostrow, Andrew Zachary, Aparicio, Oscar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252487/
https://www.ncbi.nlm.nih.gov/pubmed/37298223
http://dx.doi.org/10.3390/ijms24119271