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Broadly Applicable Control Approaches Improve Accuracy of ChIP-Seq Data
Chromatin ImmunoPrecipitation (ChIP) is a widely used method for the analysis of protein–DNA interactions in vivo; however, ChIP has pitfalls, particularly false-positive signal enrichment that permeates the data. We have developed a new approach to control for non-specific enrichment in ChIP that i...
Autores principales: | Petrie, Meghan V., He, Yiwei, Gan, Yan, Ostrow, Andrew Zachary, Aparicio, Oscar M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252487/ https://www.ncbi.nlm.nih.gov/pubmed/37298223 http://dx.doi.org/10.3390/ijms24119271 |
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