Palbociclib-Induced Cellular Senescence Is Modulated by the mTOR Complex 1 and Autophagy

Despite not dividing, senescent cells acquire the ability to synthesize and secrete a plethora of bioactive molecules, a feature known as the senescence-associated secretory phenotype (SASP). In addition, senescent cells often upregulate autophagy, a catalytic process that improves cell viability in...

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Detalles Bibliográficos
Autores principales: Cayo, Angel, Venturini, Whitney, Rebolledo-Mira, Danitza, Moore-Carrasco, Rodrigo, Herrada, Andrés A., Nova-Lamperti, Estefanía, Valenzuela, Claudio, Brown, Nelson E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252531/
https://www.ncbi.nlm.nih.gov/pubmed/37298236
http://dx.doi.org/10.3390/ijms24119284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252531/
https://www.ncbi.nlm.nih.gov/pubmed/37298236
http://dx.doi.org/10.3390/ijms24119284

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