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Collagen VI Is a Gi-Biased Ligand of the Adhesion GPCR GPR126/ADGRG6

GPR126/ADGRG6, a member of the adhesion G-protein-coupled receptor family, balances cell differentiation and proliferation through fine-tuning of intracellular cAMP levels, which is achieved through coupling to Gs and Gi proteins. While GPR126-mediated cAMP increase has been proven to be essential f...

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Detalles Bibliográficos
Autores principales: Wilde, Caroline, Chaudhry, Paulomi Mehta, Luo, Rong, Simon, Kay-Uwe, Piao, Xianhua, Liebscher, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252604/
https://www.ncbi.nlm.nih.gov/pubmed/37296671
http://dx.doi.org/10.3390/cells12111551