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Collagen VI Is a Gi-Biased Ligand of the Adhesion GPCR GPR126/ADGRG6
GPR126/ADGRG6, a member of the adhesion G-protein-coupled receptor family, balances cell differentiation and proliferation through fine-tuning of intracellular cAMP levels, which is achieved through coupling to Gs and Gi proteins. While GPR126-mediated cAMP increase has been proven to be essential f...
Autores principales: | Wilde, Caroline, Chaudhry, Paulomi Mehta, Luo, Rong, Simon, Kay-Uwe, Piao, Xianhua, Liebscher, Ines |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252604/ https://www.ncbi.nlm.nih.gov/pubmed/37296671 http://dx.doi.org/10.3390/cells12111551 |
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