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MicroRNA-29a Mitigates Laminectomy-Induced Spinal Epidural Fibrosis and Gait Dysregulation by Repressing TGF-β1 and IL-6

Spinal epidural fibrosis is one of the typical features attributable to failed back surgery syndrome, with excessive scar development in the dura and nerve roots. The microRNA-29 family (miR-29s) has been found to act as a fibrogenesis-inhibitory factor that reduces fibrotic matrix overproduction in...

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Detalles Bibliográficos
Autores principales: Lin, I-Ting, Lin, Yu-Han, Lian, Wei-Shiung, Wang, Feng-Sheng, Wu, Re-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252628/
https://www.ncbi.nlm.nih.gov/pubmed/37298111
http://dx.doi.org/10.3390/ijms24119158