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MicroRNA-29a Mitigates Laminectomy-Induced Spinal Epidural Fibrosis and Gait Dysregulation by Repressing TGF-β1 and IL-6
Spinal epidural fibrosis is one of the typical features attributable to failed back surgery syndrome, with excessive scar development in the dura and nerve roots. The microRNA-29 family (miR-29s) has been found to act as a fibrogenesis-inhibitory factor that reduces fibrotic matrix overproduction in...
Autores principales: | Lin, I-Ting, Lin, Yu-Han, Lian, Wei-Shiung, Wang, Feng-Sheng, Wu, Re-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252628/ https://www.ncbi.nlm.nih.gov/pubmed/37298111 http://dx.doi.org/10.3390/ijms24119158 |
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