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The Impact of NAD Bioavailability on DNA Double-Strand Break Repair Capacity in Human Dermal Fibroblasts after Ionizing Radiation

Nicotinamide adenine dinucleotide (NAD) serves as a substrate for protein deacetylases sirtuins and poly(ADP-ribose) polymerases, which are involved in the regulation of DNA double-strand break (DSB) repair molecular machinery by various mechanisms. However, the impact of NAD bioavailability on DSB...

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Detalles Bibliográficos
Autores principales: Svetlova, Maria, Solovjeva, Ljudmila, Kropotov, Andrey, Nikiforov, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252650/
https://www.ncbi.nlm.nih.gov/pubmed/37296639
http://dx.doi.org/10.3390/cells12111518