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Mustard Gas Exposure Actuates SMAD2/3 Signaling to Promote Myofibroblast Generation in the Cornea

Sulfur mustard gas (SM) is a vesicating and alkylating agent used as a chemical weapon in many mass-casualty incidents since World War I. Ocular injuries were reported in >90% of exposed victims. The mechanisms underlying SM-induced blindness remain elusive. This study tested the hypothesis that...

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Detalles Bibliográficos
Autores principales: Sinha, Nishant R., Tripathi, Ratnakar, Balne, Praveen K., Suleiman, Laila, Simkins, Katherine, Chaurasia, Shyam S., Mohan, Rajiv R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252656/
https://www.ncbi.nlm.nih.gov/pubmed/37296653
http://dx.doi.org/10.3390/cells12111533