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The Scarface Score: Deciphering Response to DNA Damage Agents in High-Grade Serous Ovarian Cancer—A GEICO Study

SIMPLE SUMMARY: The response of high-grade serous ovarian cancer (HGSOC) to DNA-damaging agents largely depends on tumor genomic instability (GI), a phenomenon that affects the entire genome. Nowadays, surrogate biomarkers of this phenomenon, such as BRCA-gene mutations, are used in clinical practic...

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Detalles Bibliográficos
Autores principales: Fernández-Serra, Antonio, López-Reig, Raquel, Márquez, Raúl, Gallego, Alejandro, de Sande, Luís Miguel, Yubero, Alfonso, Pérez-Segura, Cristina, Ramchandani-Vaswani, Avinash, Barretina-Ginesta, María Pilar, Mendizábal, Elsa, Esteban, Carmen, Gálvez, Fernando, Sánchez-Heras, Ana Beatriz, Guerra-Alía, Eva María, Gaba, Lydia, Quindós, María, Palacio, Isabel, Alarcón, Jesús, Oaknin, Ana, Aliaga, Jessica, Ramírez-Calvo, Marta, García-Casado, Zaida, Romero, Ignacio, López-Guerrero, José Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252660/
https://www.ncbi.nlm.nih.gov/pubmed/37296992
http://dx.doi.org/10.3390/cancers15113030