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Neuropathic-like Nociception and Spinal Cord Neuroinflammation Are Dependent on the TRPA1 Channel in Multiple Sclerosis Models in Mice

Background: Transient receptor potential ankyrin 1 (TRPA1) activation is implicated in neuropathic pain-like symptoms. However, whether TRPA1 is solely implicated in pain-signaling or contributes to neuroinflammation in multiple sclerosis (MS) is unknown. Here, we evaluated the TRPA1 role in neuroin...

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Detalles Bibliográficos
Autores principales: Dalenogare, Diéssica Padilha, Souza Monteiro de Araújo, Daniel, Landini, Lorenzo, Titiz, Mustafa, De Siena, Gaetano, De Logu, Francesco, Geppetti, Pierangelo, Nassini, Romina, Trevisan, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252670/
https://www.ncbi.nlm.nih.gov/pubmed/37296632
http://dx.doi.org/10.3390/cells12111511