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Zn(2+) and Cu(2+) Interaction with the Recognition Interface of ACE2 for SARS-CoV-2 Spike Protein

The spike protein (S) of SARS-CoV-2 is able to bind to the human angiotensin-converting enzyme 2 (ACE2) receptor with a much higher affinity compared to other coronaviruses. The binding interface between the ACE2 receptor and the spike protein plays a critical role in the entry mechanism of the SARS...

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Detalles Bibliográficos
Autores principales: Pelucelli, Alessio, Peana, Massimiliano, Orzeł, Bartosz, Piasta, Karolina, Gumienna-Kontecka, Elzbieta, Medici, Serenella, Zoroddu, Maria Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252707/
https://www.ncbi.nlm.nih.gov/pubmed/37298154
http://dx.doi.org/10.3390/ijms24119202