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Extracellular Vesicle Depletion Protocols of Foetal Bovine Serum Influence Umbilical Cord Mesenchymal Stromal Cell Phenotype, Immunomodulation, and Particle Release

The immunomodulatory properties of MSCs can be recreated using their extracellular vesicles (EVs). Yet, the true capabilities of the MSC EVs cannot be distinguished from contaminating bovine EVs and protein derived from supplemental foetal bovine serum (FBS). FBS EV depletion protocols can minimise...

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Detalles Bibliográficos
Autores principales: Davies, Rebecca, Allen, Shannen, Mennan, Claire, Platt, Mark, Wright, Karina, Kehoe, Oksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252846/
https://www.ncbi.nlm.nih.gov/pubmed/37298194
http://dx.doi.org/10.3390/ijms24119242