Pevonedistat Inhibits SOX2 Expression and Sphere Formation but Also Drives the Induction of Terminal Differentiation Markers and Apoptosis within Arsenite-Transformed Urothelial Cells

Urothelial cancer (UC) is a common malignancy and its development is associated with arsenic exposure. Around 25% of diagnosed UC cases are muscle invasive (MIUC) and are frequently associated with squamous differentiation. These patients commonly develop cisplatin (CIS) resistance and have poor pro...

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Detalles Bibliográficos
Autores principales: Mehus, Aaron A., Jones, Madison, Trahan, Mason, Kinnunen, Kaija, Berwald, Kaitlyn, Lindner, Becker, Al-Marsoummi, Sarmad, Zhou, Xu Dong, Garrett, Scott H., Sens, Donald A., Sens, Mary Ann, Somji, Seema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252886/
https://www.ncbi.nlm.nih.gov/pubmed/37298099
http://dx.doi.org/10.3390/ijms24119149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252886/
https://www.ncbi.nlm.nih.gov/pubmed/37298099
http://dx.doi.org/10.3390/ijms24119149

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