Pharmacometabolic Effects of Pteryxin and Valproate on Pentylenetetrazole-Induced Seizures in Zebrafish Reveal Vagus Nerve Stimulation

Zebrafish (Danio rerio) assays provide a versatile pharmacological platform to test compounds on a wide range of behaviors in a whole organism. A major challenge lies in the lack of knowledge about the bioavailability and pharmacodynamic effects of bioactive compounds in this model organism. Here, w...

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Detalles Bibliográficos
Autores principales: Skiba, Adrianna, Pellegata, Daniele, Morozova, Veronika, Kozioł, Ewelina, Budzyńska, Barbara, Lee, Simon Ming-Yuen, Gertsch, Jürg, Skalicka-Woźniak, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252891/
https://www.ncbi.nlm.nih.gov/pubmed/37296660
http://dx.doi.org/10.3390/cells12111540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252891/
https://www.ncbi.nlm.nih.gov/pubmed/37296660
http://dx.doi.org/10.3390/cells12111540

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