Cargando…
Pharmacometabolic Effects of Pteryxin and Valproate on Pentylenetetrazole-Induced Seizures in Zebrafish Reveal Vagus Nerve Stimulation
Zebrafish (Danio rerio) assays provide a versatile pharmacological platform to test compounds on a wide range of behaviors in a whole organism. A major challenge lies in the lack of knowledge about the bioavailability and pharmacodynamic effects of bioactive compounds in this model organism. Here, w...
Autores principales: | Skiba, Adrianna, Pellegata, Daniele, Morozova, Veronika, Kozioł, Ewelina, Budzyńska, Barbara, Lee, Simon Ming-Yuen, Gertsch, Jürg, Skalicka-Woźniak, Krystyna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252891/ https://www.ncbi.nlm.nih.gov/pubmed/37296660 http://dx.doi.org/10.3390/cells12111540 |
Ejemplares similares
-
Evaluation of the Antiseizure Activity of Endemic Plant Halfordia kendack Guillaumin and Its Main Constituent, Halfordin, on a Zebrafish Pentylenetetrazole (PTZ)-Induced Seizure Model
por: Skiba, Adrianna, et al.
Publicado: (2023) -
Neuropsychopharmacological profiling of scoparone in mice
por: Kowalczyk, Joanna, et al.
Publicado: (2022) -
Xanthotoxin reverses Parkinson’s disease-like symptoms in zebrafish larvae and mice models: a comparative study
por: Kozioł, Ewelina, et al.
Publicado: (2020) -
Imperatorin–pharmacological meaning and analytical clues: profound investigation
por: Kozioł, Ewelina, et al.
Publicado: (2016) -
Role of cinnarizine and nifedipine on anticonvulsant effect of sodium valproate and carbamazepine in maximal electroshock and pentylenetetrazole model of seizures in mice
por: Brahmane, Ranjana I., et al.
Publicado: (2010)