Significance of Astragaloside IV from the Roots of Astragalus mongholicus as an Acetylcholinesterase Inhibitor—From the Computational and Biomimetic Analyses to the In Vitro and In Vivo Studies of Safety

The main aim of the study was to assess the acetylcholinesterase-inhibitory potential of triterpenoid saponins (astragalosides) found in the roots of Astragalus mongholicus. For this purpose, the TLC bioautography method was applied and then the IC(50) values were calculated for astragalosides II, I...

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Detalles Bibliográficos
Autores principales: Stępnik, Katarzyna, Kukula-Koch, Wirginia, Plazinski, Wojciech, Gawel, Kinga, Gaweł-Bęben, Katarzyna, Khurelbat, Daariimaa, Boguszewska-Czubara, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252989/
https://www.ncbi.nlm.nih.gov/pubmed/37298103
http://dx.doi.org/10.3390/ijms24119152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252989/
https://www.ncbi.nlm.nih.gov/pubmed/37298103
http://dx.doi.org/10.3390/ijms24119152

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