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Significance of Astragaloside IV from the Roots of Astragalus mongholicus as an Acetylcholinesterase Inhibitor—From the Computational and Biomimetic Analyses to the In Vitro and In Vivo Studies of Safety
The main aim of the study was to assess the acetylcholinesterase-inhibitory potential of triterpenoid saponins (astragalosides) found in the roots of Astragalus mongholicus. For this purpose, the TLC bioautography method was applied and then the IC(50) values were calculated for astragalosides II, I...
Autores principales: | Stępnik, Katarzyna, Kukula-Koch, Wirginia, Plazinski, Wojciech, Gawel, Kinga, Gaweł-Bęben, Katarzyna, Khurelbat, Daariimaa, Boguszewska-Czubara, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10252989/ https://www.ncbi.nlm.nih.gov/pubmed/37298103 http://dx.doi.org/10.3390/ijms24119152 |
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