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Epigenetic Histone Methylation of PPARγ and CPT1A Signaling Contributes to Betahistine Preventing Olanzapine-Induced Dyslipidemia

As a partial histamine H1 receptor agonist and H3 antagonist, betahistine has been reported to partially prevent olanzapine-induced dyslipidemia and obesity through a combination therapy, although the underlying epigenetic mechanisms are still not known. Recent studies have revealed that histone reg...

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Detalles Bibliográficos
Autores principales: Su, Yueqing, Deng, Chao, Liu, Xuemei, Lian, Jiamei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253033/
https://www.ncbi.nlm.nih.gov/pubmed/37298094
http://dx.doi.org/10.3390/ijms24119143