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Correlated Target Search by Vaccinia Virus Uracil–DNA Glycosylase, a DNA Repair Enzyme and a Processivity Factor of Viral Replication Machinery

The protein encoded by the vaccinia virus D4R gene has base excision repair uracil–DNA N-glycosylase (vvUNG) activity and also acts as a processivity factor in the viral replication complex. The use of a protein unlike PolN/PCNA sliding clamps is a unique feature of orthopoxviral replication, provid...

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Detalles Bibliográficos
Autores principales: Diatlova, Evgeniia A., Mechetin, Grigory V., Yudkina, Anna V., Zharkov, Vasily D., Torgasheva, Natalia A., Endutkin, Anton V., Shulenina, Olga V., Konevega, Andrey L., Gileva, Irina P., Shchelkunov, Sergei N., Zharkov, Dmitry O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253040/
https://www.ncbi.nlm.nih.gov/pubmed/37298065
http://dx.doi.org/10.3390/ijms24119113