Adenoviral Transfer of Human Aquaporin-8 Gene to Mouse Liver Improves Ammonia-Derived Ureagenesis

We previously reported that, in cultured hepatocytes, mitochondrial aquaporin-8 (AQP8) channels facilitate the conversion of ammonia to urea and that the expression of human AQP8 (hAQP8) enhances ammonia-derived ureagenesis. In this study, we evaluated whether hepatic gene transfer of hAQP8 improves...

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Detalles Bibliográficos
Autores principales: Capiglioni, Alejo M., Capitani, María C., Marrone, Julieta, Marinelli, Raúl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253139/
https://www.ncbi.nlm.nih.gov/pubmed/37296655
http://dx.doi.org/10.3390/cells12111535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253139/
https://www.ncbi.nlm.nih.gov/pubmed/37296655
http://dx.doi.org/10.3390/cells12111535

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