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Targeting BET Proteins Decreases Hyaluronidase-1 in Pancreatic Cancer

Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by the presence of dense stroma that is enriched in hyaluronan (HA), with increased HA levels associated with more aggressive disease. Increased levels of the HA-degrading enzymes hyaluronidases (HYALs) are also associated with tum...

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Detalles Bibliográficos
Autores principales: Kumar, Krishan, Kanojia, Deepak, Bentrem, David J., Hwang, Rosa F., Butchar, Jonathan P., Tridandapani, Susheela, Munshi, Hidayatullah G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253193/
https://www.ncbi.nlm.nih.gov/pubmed/37296612
http://dx.doi.org/10.3390/cells12111490