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Targeting BET Proteins Decreases Hyaluronidase-1 in Pancreatic Cancer
Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by the presence of dense stroma that is enriched in hyaluronan (HA), with increased HA levels associated with more aggressive disease. Increased levels of the HA-degrading enzymes hyaluronidases (HYALs) are also associated with tum...
Autores principales: | Kumar, Krishan, Kanojia, Deepak, Bentrem, David J., Hwang, Rosa F., Butchar, Jonathan P., Tridandapani, Susheela, Munshi, Hidayatullah G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253193/ https://www.ncbi.nlm.nih.gov/pubmed/37296612 http://dx.doi.org/10.3390/cells12111490 |
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