Investigating the Role of Heparanase in Breast Cancer Development Utilising the MMTV-PyMT Murine Model of Mammary Carcinoma

SIMPLE SUMMARY: Heparanase (HPSE) has been demonstrated to enhance the progression and metastasis of solid tumours, leading to a poor clinical prognosis. However, robust genetic ablation animal models to investigate the role of HPSE in breast cancer have not been described. The aim of this study was...

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Detalles Bibliográficos
Autores principales: Jayatilleke, Krishnath M., Duivenvoorden, Hendrika M., Ryan, Gemma F., Parker, Belinda S., Hulett, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253202/
https://www.ncbi.nlm.nih.gov/pubmed/37297024
http://dx.doi.org/10.3390/cancers15113062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253202/
https://www.ncbi.nlm.nih.gov/pubmed/37297024
http://dx.doi.org/10.3390/cancers15113062

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