Genome-Wide Screening in Human Embryonic Stem Cells Highlights the Hippo Signaling Pathway as Granting Synthetic Viability in ATM Deficiency

ATM depletion is associated with the multisystemic neurodegenerative syndrome ataxia–telangiectasia (A–T). The exact linkage between neurodegeneration and ATM deficiency has not been established yet, and no treatment is currently available. In this study, we aimed to identify synthetic viable genes...

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Detalles Bibliográficos
Autores principales: Viner-Breuer, Ruth, Golan-Lev, Tamar, Benvenisty, Nissim, Goldberg, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253227/
https://www.ncbi.nlm.nih.gov/pubmed/37296624
http://dx.doi.org/10.3390/cells12111503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253227/
https://www.ncbi.nlm.nih.gov/pubmed/37296624
http://dx.doi.org/10.3390/cells12111503

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