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PNPLA3-I148M Variant Promotes the Progression of Liver Fibrosis by Inducing Mitochondrial Dysfunction

Patatin-like phospholipase domain-containing 3 (PNPLA3) rs738409 polymorphism (I148M) is strongly associated with non-alcoholic steatohepatitis and advanced fibrosis; however, the underlying mechanisms remain largely unknown. In this study, we investigated the effect of PNPLA3-I148M on the activatio...

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Detalles Bibliográficos
Autores principales:	Gou, Yusong, Wang, Lifei, Zhao, Jinhan, Xu, Xiaoyi, Xu, Hangfei, Xie, Fang, Wang, Yanjun, Feng, Yingmei, Zhang, Jing, Zhang, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253263/ https://www.ncbi.nlm.nih.gov/pubmed/37298640 http://dx.doi.org/10.3390/ijms24119681

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