Empagliflozin Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Rats by Modulating Sesn2/AMPK/Nrf2 Signaling and Targeting Ferroptosis and Autophagy

Pulmonary fibrosis (PF) is a life-threatening disorder that severely disrupts normal lung architecture and function, resulting in severe respiratory failure and death. It has no definite treatment. Empagliflozin (EMPA), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, has protective potential in...

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Detalles Bibliográficos
Autores principales: El-Horany, Hemat El-Sayed, Atef, Marwa Mohamed, Abdel Ghafar, Muhammad Tarek, Fouda, Mohamed. H., Nasef, Nahla Anas, Hegab, Islam Ibrahim, Helal, Duaa S., Elseady, Walaa, Hafez, Yasser Mostafa, Hagag, Rasha Youssef, Seleem, Monira Abdelmoaty, Saleh, Mai Mahmoud, Radwan, Doaa A., Abd El-Lateef, Amal Ezzat, Abd-Ellatif, Rania Nagi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253289/
https://www.ncbi.nlm.nih.gov/pubmed/37298433
http://dx.doi.org/10.3390/ijms24119481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253289/
https://www.ncbi.nlm.nih.gov/pubmed/37298433
http://dx.doi.org/10.3390/ijms24119481

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