Splicing Modulators Are Involved in Human Polyglutamine Diversification via Protein Complexes Shuttling between Nucleus and Cytoplasm

Length polymorphisms of polyglutamine (polyQs) in triplet-repeat-disease-causing genes have diversified during primate evolution despite them conferring a risk of human-specific diseases. To explain the evolutionary process of this diversification, there is a need to focus on mechanisms by which rap...

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Detalles Bibliográficos
Autor principal: Shimada, Makoto K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253306/
https://www.ncbi.nlm.nih.gov/pubmed/37298574
http://dx.doi.org/10.3390/ijms24119622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253306/
https://www.ncbi.nlm.nih.gov/pubmed/37298574
http://dx.doi.org/10.3390/ijms24119622

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