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A Combination of the Immunotherapeutic Drug Anti-Programmed Death 1 with Lenalidomide Enhances Specific T Cell Immune Responses against Acute Myeloid Leukemia Cells

Immune checkpoint inhibitors can block inhibitory molecules on the surface of T cells, switching them from an exhausted to an active state. One of these inhibitory immune checkpoints, programmed cell death protein 1 (PD-1) is expressed on T cell subpopulations in acute myeloid leukemia (AML). PD-1 e...

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Detalles Bibliográficos
Autores principales: Guinn, Barbara-ann, Schuler, Patrick J., Schrezenmeier, Hubert, Hofmann, Susanne, Weiss, Johanna, Bulach, Christiane, Götz, Marlies, Greiner, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253334/
https://www.ncbi.nlm.nih.gov/pubmed/37298237
http://dx.doi.org/10.3390/ijms24119285