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Genetic Targeting of dSAMTOR, A Negative dTORC1 Regulator, during Drosophila Aging: A Tissue-Specific Pathology

mTORC1 regulates mammalian cell metabolism and growth in response to diverse environmental stimuli. Nutrient signals control the localization of mTORC1 onto lysosome surface scaffolds that are critically implicated in its amino acid-dependent activation. Arginine, leucine and S-adenosyl-methionine (...

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Detalles Bibliográficos
Autores principales: Katarachia, Stamatia A., Markaki, Sophia P., Velentzas, Athanassios D., Stravopodis, Dimitrios J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253371/
https://www.ncbi.nlm.nih.gov/pubmed/37298625
http://dx.doi.org/10.3390/ijms24119676