Metformin Counteracts the Deleterious Effects of Methylglyoxal on Ovalbumin-Induced Airway Eosinophilic Inflammation and Remodeling

Exposure to methylglyoxal (MGO) increases the levels of receptor for advanced glycation end products (RAGE) and reactive-oxygen species (ROS) in mouse airways, exacerbating the inflammatory responses. Metformin scavenges MGO in plasma of diabetic individuals. We investigated if amelioration by metfo...

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Detalles Bibliográficos
Autores principales: Medeiros, Matheus L., Oliveira, Akila L., Mello, Glaucia C., Antunes, Edson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253375/
https://www.ncbi.nlm.nih.gov/pubmed/37298498
http://dx.doi.org/10.3390/ijms24119549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253375/
https://www.ncbi.nlm.nih.gov/pubmed/37298498
http://dx.doi.org/10.3390/ijms24119549

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