Cargando…

Metformin Counteracts the Deleterious Effects of Methylglyoxal on Ovalbumin-Induced Airway Eosinophilic Inflammation and Remodeling

Exposure to methylglyoxal (MGO) increases the levels of receptor for advanced glycation end products (RAGE) and reactive-oxygen species (ROS) in mouse airways, exacerbating the inflammatory responses. Metformin scavenges MGO in plasma of diabetic individuals. We investigated if amelioration by metfo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Medeiros, Matheus L., Oliveira, Akila L., Mello, Glaucia C., Antunes, Edson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253375/ https://www.ncbi.nlm.nih.gov/pubmed/37298498 http://dx.doi.org/10.3390/ijms24119549

Ejemplares similares

Methylglyoxal Exacerbates Lipopolysaccharide-Induced Acute Lung Injury via RAGE-Induced ROS Generation: Protective Effects of Metformin
por: Medeiros, Matheus L, et al.
Publicado: (2021)

Enhanced RAGE Expression and Excess Reactive-Oxygen Species Production Mediates Rho Kinase-Dependent Detrusor Overactivity After Methylglyoxal Exposure
por: Oliveira, Akila L., et al.
Publicado: (2022)

Glucagon reduces airway hyperreactivity, inflammation, and remodeling induced by ovalbumin
por: Insuela, Daniella B. R., et al.
Publicado: (2019)

Methylglyoxal, a Reactive Glucose Metabolite, Induces Bladder Overactivity in Addition to Inflammation in Mice
por: de Oliveira, Mariana G., et al.
Publicado: (2020)

Ding Chuan Tang Attenuates Airway Inflammation and Eosinophil Infiltration in Ovalbumin-Sensitized Asthmatic Mice
por: Ma, Jason, et al.
Publicado: (2021)

Exercise Counteracts the Deleterious Effects of Cancer Cachexia
por: Tsitkanou, Stavroula, et al.
Publicado: (2022)

Has2 Regulates the Development of Ovalbumin-Induced Airway Remodeling and Steroid Insensitivity in Mice
por: Sherpa, Mingma Thsering, et al.
Publicado: (2022)

Saponin-enriched extract of Asparagus cochinchinensis alleviates airway inflammation and remodeling in ovalbumin-induced asthma model
por: Sung, Ji-Eun, et al.
Publicado: (2017)

Protective effects of ascorbic acid and calcitriol combination on airway remodelling in ovalbumin-induced chronic asthma
por: Kianian, Farzaneh, et al.
Publicado: (2020)

Targeting the cannabinoid system to counteract the deleterious effects of stress in Alzheimer’s disease
por: Shade, Ronnie D., et al.
Publicado: (2022)

Role of Matrix Metalloproteinase-2 in Eosinophil-Mediated Airway Remodeling
por: Kuwabara, Yu, et al.
Publicado: (2018)

Eosinophil-derived neurotoxin enhances airway remodeling in eosinophilic chronic rhinosinusitis and correlates with disease severity
por: Tsuda, Takeshi, et al.
Publicado: (2018)

Syndecan-1 Amplifies Ovalbumin-Induced Airway Remodeling by Strengthening TGFβ1/Smad3 Action
por: Zhang, Dong, et al.
Publicado: (2021)

Metformin Attenuates the Exacerbation of the Allergic Eosinophilic Inflammation in High Fat-Diet-Induced Obesity in Mice
por: Calixto, Marina Ciarallo, et al.
Publicado: (2013)

The administration of clopidogrel attenuates airway hyperresponsiveness and airway inflammation in an ovalbumin specific allergic asthma model
por: Trinh, Hoang Kim Tu, et al.
Publicado: (2015)

Akkermansia muciniphila counteracts the deleterious effects of dietary emulsifiers on microbiota and host metabolism
por: Daniel, Noëmie, et al.
Publicado: (2023)

Ovalbumin Sensitization Changes the Inflammatory Response to Subsequent Parainfluenza Infection: Eosinophils Mediate Airway Hyperresponsiveness, M(2) Muscarinic Receptor Dysfunction, and Antiviral Effects
por: Adamko, Darryl J., et al.
Publicado: (1999)

Metformin prevents methylglyoxal-induced apoptosis by suppressing oxidative stress in vitro and in vivo
por: Wang, Gang, et al.
Publicado: (2022)

Suppression of Eosinophil Integrins Prevents Remodeling of Airway Smooth Muscle in Asthma
por: Januskevicius, Andrius, et al.
Publicado: (2017)

Re-Challenge with Ovalbumin Failed to Induce Bronchial Asthma in Mice with Eosinophilic Bronchitis
por: Chen, Liyan, et al.
Publicado: (2013)

Concomitant Exposure to Ovalbumin and Endotoxin Augments Airway Inflammation but Not Airway Hyperresponsiveness in a Murine Model of Asthma
por: Mac Sharry, John, et al.
Publicado: (2014)

TRIF Deficiency does not Affect Severity of Ovalbumin-induced Airway Inflammation in Mice
por: Kim, Tae-Hyoun, et al.
Publicado: (2014)

Aquaporin-3 potentiates allergic airway inflammation in ovalbumin-induced murine asthma
por: Ikezoe, Kohei, et al.
Publicado: (2016)

Inhibitory Effect of Sihuangxiechai Decoction on Ovalbumin-Induced Airway Inflammation in Guinea Pigs
por: Huang, Xue Ping, et al.
Publicado: (2014)

Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust
por: Warren, Kristi J., et al.
Publicado: (2019)

Eosinophilic airway inflammation in COPD
por: Saha, Shironjit, et al.
Publicado: (2006)

The miR‐124‐3p regulates the allergic airway inflammation and remodeling in an ovalbumin‐asthmatic mouse model by inhibiting S100A4
por: Liu, Min, et al.
Publicado: (2023)

Salvinorin A Inhibits Airway Hyperreactivity Induced by Ovalbumin Sensitization
por: Rossi, Antonietta, et al.
Publicado: (2017)

Metformin Delays the Development of Atherosclerosis in Type 1 Diabetes Mellitus via the Methylglyoxal Pathway
por: Liu, Aihong, et al.
Publicado: (2020)

Effects of crocin and metformin on methylglyoxal-induced reproductive system dysfunction in diabetic male mice
por: Kheirollahi Khorasani, Maryam, et al.
Publicado: (2021)

Immunolocalization of NLRP3 Inflammasome in Normal Murine Airway Epithelium and Changes following Induction of Ovalbumin-Induced Airway Inflammation
por: Tran, Hai B., et al.
Publicado: (2012)

CCL4 Regulates Eosinophil Activation in Eosinophilic Airway Inflammation
por: Chu, Hanh Hong, et al.
Publicado: (2022)

Remodeling of the lower and upper airways
por: de Toledo Leme Constantino, Guilherme, et al.
Publicado: (2015)

Toxic and adjuvant effects of silica nanoparticles on ovalbumin-induced allergic airway inflammation in mice
por: Han, Heejae, et al.
Publicado: (2016)

Stigmasterol Modulates Allergic Airway Inflammation in Guinea Pig Model of Ovalbumin-Induced Asthma
por: Antwi, Aaron Opoku, et al.
Publicado: (2017)

Interleukin-22 attenuates allergic airway inflammation in ovalbumin-induced asthma mouse model
por: Wang, Jingru, et al.
Publicado: (2021)

Clinical Outcome of Eosinophilic Airway Inflammation in Chronic Airway Diseases Including Nonasthmatic Eosinophilic Bronchitis
por: Cho, Jaeyoung, et al.
Publicado: (2018)

Salt Potentiates Methylamine Counteraction System to Offset the Deleterious Effects of Urea on Protein Stability and Function
por: Rahman, Safikur, et al.
Publicado: (2015)

Regular and Moderate Exercise Counteracts the Decline of Antioxidant Protection but Not Methylglyoxal-Dependent Glycative Burden in the Ovary of Reproductively Aging Mice
por: Falone, S., et al.
Publicado: (2016)

The Role of Autophagy in Eosinophilic Airway Inflammation
por: Lee, Jinju, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5dkbc496oq5h88u1r3ud0j6geh