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Potentiating the Cross-Reactive IFN-γ T Cell and Polyfunctional T Cell Responses by Heterologous GX-19N DNA Booster in Mice Primed with Either a COVID-19 mRNA Vaccine or Inactivated Vaccine

Waning vaccine-induced immunity, coupled with the emergence of SARS-CoV-2 variants, has inspired the widespread implementation of COVID-19 booster vaccinations. Here, we evaluated the potential of the GX-19N DNA vaccine as a heterologous booster to enhance the protective immune response to SARS-CoV-...

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Detalles Bibliográficos
Autores principales: Seo, Yong Bok, Ko, Ara, Shin, Duckhyang, Kim, Junyoung, Suh, You Suk, Na, Juyoung, Ryu, Ji In, Lee, Suyeon, Oh, Min Ji, Sung, Young Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253410/
https://www.ncbi.nlm.nih.gov/pubmed/37298704
http://dx.doi.org/10.3390/ijms24119753