When Characteristics of Clinical Trials Require Per-Protocol as Well as Intention-to-Treat Outcomes to Draw Reliable Conclusions: Three Examples

Under exceptional circumstances, including high rates of protocol non-compliance, per-protocol (PP) analysis can better indicate the real-world benefits of a medical intervention than intention-to-treat (ITT) analysis. Exemplifying this, the first randomized clinical trial (RCT) considered found tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Scheim, David E., Aldous, Colleen, Osimani, Barbara, Fordham, Edmund J., Hoy, Wendy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253430/
https://www.ncbi.nlm.nih.gov/pubmed/37297820
http://dx.doi.org/10.3390/jcm12113625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253430/
https://www.ncbi.nlm.nih.gov/pubmed/37297820
http://dx.doi.org/10.3390/jcm12113625

Ejemplares similares