Structural and Biological Features of G-Quadruplex Aptamers as Promising Inhibitors of the STAT3 Signaling Pathway

In this paper, we investigate the structural and biological features of G-quadruplex (G4) aptamers as promising antiproliferative compounds affecting the STAT3 signalling pathway. Targeting the STAT3 protein through high-affinity ligands to reduce its levels or activity in cancer has noteworthy ther...

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Detalles Bibliográficos
Autores principales: Esposito, Veronica, Benigno, Daniela, Bello, Ivana, Panza, Elisabetta, Bucci, Mariarosaria, Virgilio, Antonella, Galeone, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253491/
https://www.ncbi.nlm.nih.gov/pubmed/37298475
http://dx.doi.org/10.3390/ijms24119524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253491/
https://www.ncbi.nlm.nih.gov/pubmed/37298475
http://dx.doi.org/10.3390/ijms24119524

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