Cargando…
Structural and Biological Features of G-Quadruplex Aptamers as Promising Inhibitors of the STAT3 Signaling Pathway
In this paper, we investigate the structural and biological features of G-quadruplex (G4) aptamers as promising antiproliferative compounds affecting the STAT3 signalling pathway. Targeting the STAT3 protein through high-affinity ligands to reduce its levels or activity in cancer has noteworthy ther...
Autores principales: | Esposito, Veronica, Benigno, Daniela, Bello, Ivana, Panza, Elisabetta, Bucci, Mariarosaria, Virgilio, Antonella, Galeone, Aldo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253491/ https://www.ncbi.nlm.nih.gov/pubmed/37298475 http://dx.doi.org/10.3390/ijms24119524 |
Ejemplares similares
-
Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads
por: Benigno, Daniela, et al.
Publicado: (2022) -
Probing the Importance of the G-Quadruplex Grooves for the Activity of the Anti-HIV-Integrase Aptamer T30923
por: Esposito, Veronica, et al.
Publicado: (2020) -
Improving the Biological Properties of Thrombin-Binding Aptamer by Incorporation of 8-Bromo-2′-Deoxyguanosine and 2′-Substituted RNA Analogues
por: Virgilio, Antonella, et al.
Publicado: (2023) -
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction
por: Festa, Carmen, et al.
Publicado: (2022) -
Aptamers Against the β-Conglutin Allergen: Insights into the Behavior of the Shortest Multimeric(Intra)Molecular DNA G-Quadruplex
por: O’ Sullivan, Ciara K., et al.
Publicado: (2021)