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α-Tocotrienol and Redox-Silent Analogs of Vitamin E Enhances Bortezomib Sensitivity in Solid Cancer Cells through Modulation of NFE2L1

Proteasome inhibitors (PIs) have emerged as an attractive novel cancer therapy. However, most solid cancers are seemingly resistant to PIs. The activation of transcription factor Nuclear factor erythroid 2 related factor-1 (NFE2L1) has been characterized as a potential resistance response to protect...

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Detalles Bibliográficos
Autores principales: Ishii, Kyota, Hido, Mayuko, Sakamura, Misaki, Virgona, Nantiga, Yano, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253528/
https://www.ncbi.nlm.nih.gov/pubmed/37298331
http://dx.doi.org/10.3390/ijms24119382