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Calpain-3 Is Not a Sodium Dependent Protease and Simply Requires Calcium for Activation
Calpain-3 (CAPN3) is a muscle-specific member of the calpain family of Ca(2+)-dependent proteases. It has been reported that CAPN3 can also be autolytically activated by Na(+) ions in the absence of Ca(2+), although this was only shown under non-physiological ionic conditions. Here we confirm that C...
Autores principales: | Wette, Stefan G., Lamb, Graham D., Murphy, Robyn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253552/ https://www.ncbi.nlm.nih.gov/pubmed/37298357 http://dx.doi.org/10.3390/ijms24119405 |
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