The Cleavage-Specific Tau 12A12mAb Exerts an Anti-Amyloidogenic Action by Modulating the Endocytic and Bioenergetic Pathways in Alzheimer’s Disease Mouse Model

Beyond deficits in hippocampal-dependent episodic memory, Alzheimer’s Disease (AD) features sensory impairment in visual cognition consistent with extensive neuropathology in the retina. 12A12 is a monoclonal cleavage specific antibody (mAb) that in vivo selectively neutralizes the AD-relevant, harm...

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Detalles Bibliográficos
Autores principales: Latina, Valentina, Atlante, Anna, Malerba, Francesca, La Regina, Federico, Balzamino, Bijorn Omar, Micera, Alessandra, Pignataro, Annabella, Stigliano, Egidio, Cavallaro, Sebastiano, Calissano, Pietro, Amadoro, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253571/
https://www.ncbi.nlm.nih.gov/pubmed/37298634
http://dx.doi.org/10.3390/ijms24119683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253571/
https://www.ncbi.nlm.nih.gov/pubmed/37298634
http://dx.doi.org/10.3390/ijms24119683

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