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The Cleavage-Specific Tau 12A12mAb Exerts an Anti-Amyloidogenic Action by Modulating the Endocytic and Bioenergetic Pathways in Alzheimer’s Disease Mouse Model
Beyond deficits in hippocampal-dependent episodic memory, Alzheimer’s Disease (AD) features sensory impairment in visual cognition consistent with extensive neuropathology in the retina. 12A12 is a monoclonal cleavage specific antibody (mAb) that in vivo selectively neutralizes the AD-relevant, harm...
Autores principales: | Latina, Valentina, Atlante, Anna, Malerba, Francesca, La Regina, Federico, Balzamino, Bijorn Omar, Micera, Alessandra, Pignataro, Annabella, Stigliano, Egidio, Cavallaro, Sebastiano, Calissano, Pietro, Amadoro, Giuseppina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253571/ https://www.ncbi.nlm.nih.gov/pubmed/37298634 http://dx.doi.org/10.3390/ijms24119683 |
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