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Conformationally Restricted Glycoconjugates Derived from Arylsulfonamides and Coumarins: New Families of Tumour-Associated Carbonic Anhydrase Inhibitors

The involvement of carbonic anhydrases (CAs) in a myriad of biological events makes the development of new inhibitors of these metalloenzymes a hot topic in current Medicinal Chemistry. In particular, CA IX and XII are membrane-bound enzymes, responsible for tumour survival and chemoresistance. Here...

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Detalles Bibliográficos
Autores principales: Martínez-Montiel, Mónica, Romero-Hernández, Laura L., Giovannuzzi, Simone, Begines, Paloma, Puerta, Adrián, Ahuja-Casarín, Ana I., Fernandes, Miguel X., Merino-Montiel, Penélope, Montiel-Smith, Sara, Nocentini, Alessio, Padrón, José M., Supuran, Claudiu T., Fernández-Bolaños, José G., López, Óscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253577/
https://www.ncbi.nlm.nih.gov/pubmed/37298353
http://dx.doi.org/10.3390/ijms24119401