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Oleoylethanolamide Treatment Modulates Both Neuroinflammation and Microgliosis, and Prevents Massive Leukocyte Infiltration to the Cerebellum in a Mouse Model of Neuronal Degeneration

Neurodegenerative diseases involve an exacerbated neuroinflammatory response led by microglia that triggers cytokine storm and leukocyte infiltration into the brain. PPARα agonists partially dampen this neuroinflammation in some models of brain insult, but neuronal loss was not the triggering cause...

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Detalles Bibliográficos
Autores principales: Pérez-Martín, Ester, Pérez-Revuelta, Laura, Barahona-López, Cristina, Pérez-Boyero, David, Alonso, José R., Díaz, David, Weruaga, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253688/
https://www.ncbi.nlm.nih.gov/pubmed/37298639
http://dx.doi.org/10.3390/ijms24119691