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Tumoricidal Activity of Simvastatin in Synergy with RhoA Inactivation in Antimigration of Clear Cell Renal Cell Carcinoma Cells

Among kidney cancers, clear cell renal cell carcinoma (ccRCC) has the highest incidence rate in adults. The survival rate of patients diagnosed as having metastatic ccRCC drastically declines even with intensive treatment. We examined the efficacy of simvastatin, a lipid-lowering drug with reduced m...

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Detalles Bibliográficos
Autores principales: Lee, Yuan-Chii Gladys, Chou, Fang-Ning, Tung, Szu-Yu, Chou, Hsiu-Chu, Ko, Tsui-Ling, Fann, Yang C., Juan, Shu-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253741/
https://www.ncbi.nlm.nih.gov/pubmed/37298689
http://dx.doi.org/10.3390/ijms24119738